Chinese Imperial Dog Club Of America
Cid Club is Dedicated to the preservation of the Chinese Imperial Dog



Juvenile Renal Dysplasia

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*More Registries accepting the CID *
IPDBA.   http://ipdba.8k.com/
UR  http://www.unitedregistry.com/
NKC.  http://www.nationalkennelclub.com/
CPR.  http://cpryourdog.com






JRD Testing
For anyone who wishes to obtain the JRD testing go to dogenes.com

Juvenile renal dysplasia (JRD) is an important category of kidney diseases in canines. Dysplasia is defined as abnormal growth or development of cells or organs. In the case of JRD the kidney fails to develop properly during embryogenesis in the womb. At birth immature structures consisting of undifferentiated fetal cells or tissue types are found in the kidney, and are persistent throughout the life of the animal.
JRD can present itself with a wide range of symptoms and pathological findings. Definitive diagnosis of JRD is done by a wedge biopsy which reveals dysplastic lesions, including abnormal ducts, and glomeruli. Individuals with an abnormal biopsy can be asymptomatic, showing no signs of the disease. On the other hand, they may present with classic signs of chronic end stage renal failure, or somewhere between these two extremes. Given this broad spectrum of symptoms affected individuals often go unnoticed, and remain in the breeding population. This is why development of a genetic test was necessary for the management and elimination of this disease.


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